P04.88 Phasic alertness deficits in brain tumor patients
نویسندگان
چکیده
منابع مشابه
Phasic alertness and residual switch costs in task switching.
Residual switch costs are deficits in task-switching performance that occur despite considerable time to prepare for a task switch. In the present study, the author investigated whether increased phasic alertness modulates residual switch costs. In 2 experiments involving the task-cuing procedure, subjects performed numerical categorization tasks on target digits, with and without an alerting s...
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An individual's ability to see and react quickly to a target stimulus is enhanced if they are alerted to the arrival of this target by a stimulus that occurs just prior in time to it. This alerting effect is thought to occur due to a phasic increase in alertness mediated by noradrenergic activity. In Alzheimer's disease (AD) there is a dysfunction in the noradrenergic system resulting in a decr...
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Participants switched between two randomly ordered discrimination tasks and each trial began with the presentation of a task cue instructing which task to execute. The authors induced phasic alertness by presenting a salient uninformative stimulus after the task cue was provided, and at variable intervals before the target stimulus was presented (Experiments 1-3) or before the task cue (Experim...
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BACKGROUND Neurofibromatosis type 1 (NF1) is one of the most common genetic disorders causing learning disabilities by mutations in the neurofibromin gene, an important inhibitor of the RAS pathway. In a mouse model of NF1, a loss of function mutation of the neurofibromin gene resulted in increased gamma aminobutyric acid (GABA)-mediated inhibition which led to decreased synaptic plasticity and...
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BACKGROUND Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice. METHODS Wechsler Adult Intelligence Scale was employed to evaluate the intelligence of 103 patients with intracranial tumor and to compare the...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2018
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/noy139.322